Presenter Information

Daniel Shaw, Biology

Faculty Sponsor(s)

Susan Swope

Abstract

If aging is a result of the degradation of the proteostasis network (PN), then treatments that support proteostasis are expected to increase lifespan. Anthocyanins have been credited with the capacity to modulate cognitive and motor function, enhance memory and having a role in preventing age-related declines in neural function. We are studying the effect of standardized purple corn extract on a transgenic strain of model organism C. elegans. We expect to see a positive effect on healthspan, resistance to oxidative stress, and mortality rate. Analysis of the composition of purple corn extract in comparison with other natural extracts shown to have longevity effects will be presented. If this natural product is shown to increase healthspan in our study, this could lead to a breakthrough for promoting healthy aging in humans in a cost effective way.

Location

Hartman Union Building Courtroom

Start Date

5-2-2019 3:00 PM

End Date

5-2-2019 4:00 PM

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May 2nd, 3:00 PM May 2nd, 4:00 PM

The Effect of Anthocyanin-Rich Purple Corn Extract on the Healthspan of Caenorhabditis elegans

Hartman Union Building Courtroom

If aging is a result of the degradation of the proteostasis network (PN), then treatments that support proteostasis are expected to increase lifespan. Anthocyanins have been credited with the capacity to modulate cognitive and motor function, enhance memory and having a role in preventing age-related declines in neural function. We are studying the effect of standardized purple corn extract on a transgenic strain of model organism C. elegans. We expect to see a positive effect on healthspan, resistance to oxidative stress, and mortality rate. Analysis of the composition of purple corn extract in comparison with other natural extracts shown to have longevity effects will be presented. If this natural product is shown to increase healthspan in our study, this could lead to a breakthrough for promoting healthy aging in humans in a cost effective way.